Acute Normovolemic Hemodilution in Cardiac Surgery
نویسندگان
چکیده
منابع مشابه
Does acute normovolemic hemodilution work in cardiac surgery?
To the Editor:—In a recent article by Höhn et al., it was concluded that acute normovolemic hemodilution (ANH) in addition to aprotinin was not beneficial in preventing allogeneic blood transfusions compared to aprotinin alone in cardiac surgery. In this randomized, controlled trial, the patients were hemodiluted to a hematocrit of 28% pre–cardiopulmonary bypass (CPB). The transfusion threshold...
متن کاملHemodynamic compensation during acute normovolemic hemodilution.
To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...
متن کاملHemodynamic Compensation during Acute Normovolemic Hemodilution
To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...
متن کاملAcute Normovolemic Hemodilution: A Practical Approach
Justifications: Perioperative allogeneic blood transfusion can be reduced or even completely avoided by using a set of different strategies: meticulous hemostasis, the use of pharmaceutical agents that assist in the process of coagulation/ fibrinolysis, the use of blood substitutes, induced hypotension, preoperative autologous blood donation, collection and reinfusion of autologous blood during...
متن کاملAcute decrease in renal microvascular PO2 during acute normovolemic hemodilution.
Large differences in the tolerance of organ systems to conditions of decreased O(2) delivery such as hemodilution exist. The kidney receives approximately 25% of the cardiac output and O(2) delivery is in excess of the oxygen demand under normal circumstances. In a rat model of acute normovolemic hemodilution (ANH), we studied the effect of reduced hematocrit on renal regional and microvascular...
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ژورنال
عنوان ژورنال: Transfusion Alternatives in Transfusion Medicine
سال: 2005
ISSN: 1295-9022,1778-428X
DOI: 10.1111/j.1778-428x.2005.tb00150.x